Safety Study of TPI-287 to Treat CBS and PSP (San Francisco)

study is seeking participants diagnosed with either PSP or CBS.

please reference Identifier: NCT02133846

For more information:




Progressive Supranuclear Palsy CorTico-Basal Syndrome Multiple System Atrophy Longitudinal Study UK

This study is currently recruiting participants who have a current clinical diagnosis of Corticobasal Degeneration (CBD)

please refer to identifier: NCT02778607

For more information:

Man, 86, gets probation in Ariz. mercy killing

I thought this was such a sad story. Quality of life verses quantity.

read more below:

Man, 86, gets probation in Ariz. mercy killing – Cincinnati Bell.

Clinical Trial Information: Bee Venom for the Treatment of Parkinson Disease (MIREILLE)NCT01341431

The purpose of this study is to evaluate the potential of using bee venom to treat Parkinson Disease. Perhaps, bee venom could treat other neurodegenerative diseases?

For more information check the link below:

Symptoms and Differences between CBGD and PSP

Rachel Gross is an  assistant professor of Neurology at the Perelman School of Medicine at the University of Pennsylvania.  She discusses  the symptoms and differences between  Cortical Basal Degeneration and Supra Nuclear Palsy. I thought this was a very informative video.

“Corticobasal Degeneration Update: Rachel Gross, MD.” YouTube. PennInstituteonAging,  24, Feb. 2012, Web.

Clinical trial information: Noninvasive Cortical Stimulation

I found a medical research study that will test alternative treatments for CBGD and PSP. Although both diseases are in the Parkinson’s family,  therapies/treatments used for Parkinson’s has little or no impact on CBGD  and PSP.

For information or to participate in the study click the link below.

Noninvasive Cortical Stimulation (rTMS) for Motor and Non-Motor Features of Progressive Supranuclear Palsy (PSP) and Corticobasal Degeneration (CBD)


Social Security and compassionate Allowances

I came across some interesting information yesterday that could provide some help for those who are diagnosed with a rare disease or disorder. At least financially it could help. The social security administration has a program called compassionate allowances for those diagnosed with a rare debilitating disease or disorder. Medical documentation needs to be be provided as proof of your condition and claims (according to the website) should be processed within three weeks.

For more information

Awe and well being

This post is a little off topic but I found it so interesting that I wanted post about it. An interesting article I found through Science discusses the correlation of feelings experienced from awe and the state of well being. I think that most of us, at some point in our lives, has experienced feelings of awe. That overwhelming feeling of wonderment, reverence, beauty or even fear. There are no words to describe it; it is sublime.  Psychologists have found that what we experience from these  profound moments impacts our well being and how we approach daily living.

To read more:
Being in Awe Can Expand Time and Enhance Well-Being

Protein Misfolding and Degenerative Diseases

Image courtesy of Wikimedia Commons

Science has found that diseases like Alzheimer’s  and Parkinson’s and even diabetes is casused not by bacteria or a virus but by protein misfolding.  Accumulation of misfolded proteins can cause disease, and unfortunately some of these diseases, known as amyloid diseases, are very common. Amyloid diseases such as Alzheimers and Parkinsons  are diseases were these proteins misfold and often accumulate. (aggregation) Protein folding is a physical process where proteins form a three dimensional structure. What causes this protein to misfold? It could be genetics or it could be just a mistake during the during the folding process.

Unfortunately, scientists have found that protein misfolding occurs a lot earlier than speculated and the symptoms can appear much later.  I suppose at this point the question is can the damage from protein misfolding be prevented or at least minimized? According to scientists, yes….but once symptoms begin to appear it is too late.

A video of different protein shapes presented by Harvard University : The Mitochondria


More information about protein misfolding:

Helicobacter Pylori and Parkinson

Helicobacter Pylori is  a bacteria that is a major cause of peptic ulcers and researchers have found a link with Parkinson’s.